An aide to Egypt's interior minister has been shot dead in Giza's Haram district, the ministry said on Tuesday.
Two assailants riding a motorcycle targeted General Mohamed Said, head of the minister's technical office, while he was leaving his home near the governorate building and Talbia police station, the interior ministry said in a statement.
The surrounding area has been cordoned off while investigations continue.
Egypt's interim Prime Minister Hazem El-Beblawy said the killing will only "fuel the authorities' determination to fight terrorism".
Offering his condolences to the victim's family, Beblawy condemned the incident, saying policemen "will keep protecting this nation no matter what."
Egypt has witnessed a surge in attacks by Islamist militants in Cairo, the Nile Delta and the Sinai Peninsula.
Four bombs exploded in Cairo the day before the third anniversary of the January 25 revolution, including one at the capital's main police headquarters. The blast killed six people and damaged the nearby Islamic Museum.
The interior minister escaped an assassination attempt in September.
A militant group called Ansar Bayt El-Maqdis has claimed responsibility for most of the attacks.